San Francisco – July 29, 2026 – Cooley advised the placement agents to Caldera Therapeutics, a privately held clinical-stage biotechnology company developing CLD-423, a potential first-in-class TL1A x IL-23p19 bispecific antibody for inflammatory bowel disease and other immune-mediated diseases, in connection with an approximately $278 million upsized private placement concurrent with its merger with Synlogic. The private placement included participation from a syndicate of leading healthcare institutional investors and mutual funds, including Bain Capital Life Sciences, TCGX, Atlas Venture, venBio Partners, Omega Funds, Blackstone Multi-Asset Investing, LAV, Wellington Management, Janus Henderson Investors, Sirenia Capital Management, Vivo Capital, several additional mutual funds and other institutional investors. Upon closing, the combined company plans to operate under the name Caldera Therapeutics, Inc. and intends to apply to trade on the Nasdaq Capital Market under the ticker symbol CALD.

Partners Denny Won, Div Gupta and Evan Leitner led the Cooley team advising the placement agents.

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