Cooley Advises MyoKardia on Collaboration with Sanofi

Palo Alto – September 23, 2014 – Cooley LLP announced today that it advised MyoKardia, Inc. on its collaboration with Sanofi S.A. to discover and develop first-of-its-kind targeted therapeutics for heritable heart diseases known as cardiomyopathies, the most common forms of heart muscle disease. The collaboration builds upon MyoKardia's pioneering science, which hopes to correct the disruptive effects that disease mutations have on heart muscle function.

The collaboration, representing one of the largest research and development commitments to genetic forms of cardiomyopathy, encompasses three MyoKardia programs. Two of these programs are focused on hypertrophic cardiomyopathy (HCM) and the other is focused on dilated cardiomyopathy (DCM). The collaboration provides up to $200 million in equity investments, milestone payments and research and development services through 2018, of which $45 million has already been received in an upfront licensing fee and an initial equity investment.

The Cooley team advising MyoKardia included partners Robert Jones, Lila Hope and Danielle Naftulin and associates Rena Kaminsky and Rose Standifer.

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